Effects of cholesterol-fat diets on pigeons susceptible and resistant to atherosclerosis.

Interactions among dietary fat, protein, and cholesterol in atherosclerosis-susceptible pigeons. Effects on serum cholesterol and aortic atherosclerosis.

SEVERAL epideiniological studies have suggested the existence of interrelationships between the occurrence of atherosclerosis and the intake of various dietary fats, proteins, and cholesterol. Thus, the work of Beveridge et al. and Ahrens et al. suggests that the level of plasma cholesterol is affected by the degree of saturation of ingested fat. On the other hand, the relationship between diet...

Interactions among dietary fat, protein, and cholesterol in atherosclerosis-susceptible pigeons. Effects on coronary atherosclerosis.

Synthetic low and high fat diets for the study of atherosclerosis in the mouse.

Diets currently used to produce atherosclerotic lesions in mice are often undefined and cause accumulation of fat in the liver and gallstone formation. Therefore, synthetic low and high fat diets of known composition were formulated in this study. A synthetic diet containing 50% sucrose, 15% cocoa butter, 1% cholesterol, and 0.5% sodium cholate was found to produce a depression in high density ...

Metabolism of low density lipoproteins by pigeon skin fibroblasts and aortic smooth muscle cells. Comparison of cells from atherosclerosis-susceptible and atherosclerosis-resistant pigeons.

Aortic smooth muscle cells from atherosclerosis-susceptible White Carneau (WC) pigeons lack a functional low density lipoprotein (LDL) receptor pathway. The purpose of the present study was to determine if atherosclerosis-resistant Show Racer pigeons (SR) shared this lack of an LDL receptor pathway and if LDL from normal and hypercholesterolemic pigeons were metabolized similarly. The amount of...

Interactive effects of increased intake of saturated fat and cholesterol on atherosclerosis in the Japanese quail (Coturnix japonica).

Increasing the energy value of diets with dietary fat, particularly fats rich in saturated fatty acids, can result in the elevation of plasma total and lipoprotein cholesterol. In the present study, experimental diets were designed to examine the effects of increasing the energy content of diets with a saturated fat source and cholesterol in a non-purified diet on hyperlipoproteinaemia and aort...